Antiprotozoal steroidal saponins from the marine sponge Pandaros acanthifolium.

@article{Regalado2010AntiprotozoalSS,
  title={Antiprotozoal steroidal saponins from the marine sponge Pandaros acanthifolium.},
  author={Erik L. Regalado and Deniz Taşdemir and Marcel Kaiser and Nadja Cachet and Philippe Amade and Olivier P. Thomas},
  journal={Journal of natural products},
  year={2010},
  volume={73 8},
  pages={
          1404-10
        }
}
The chemical composition of the Caribbean sponge Pandaros acanthifolium was reinvestigated and led to the isolation of 12 new steroidal glycosides, namely, pandarosides E-J (1-6) and their methyl esters (7-12). Their structures were determined on the basis of extensive spectroscopic analyses, including two-dimensional NMR and HRESIMS data. Like the previously isolated pandarosides A-D (13-16), the new compounds 1-12 share an unusual oxidized D-ring and a cis C/D ring junction. The absolute… Expand
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