Antiproliferative mechanisms of quercetin in rat activated hepatic stellate cells.

  title={Antiproliferative mechanisms of quercetin in rat activated hepatic stellate cells.},
  author={L. Wu and In-Wei Lu and Chi-Fu Chung and Hsing-Yu Wu and Yi-Ting Liu},
  journal={Food & function},
  volume={2 3-4},
  • L. Wu, In-Wei Lu, +2 authors Yi-Ting Liu
  • Published 2011
  • Biology, Medicine
  • Food & function
  • Quercetin, rich in fruits and vegetables, has been used as a nutritional supplement because of its anti-inflammatory and antioxidative properties. Its positive effects on anti-hepatic fibrosis have also been suggested. However the anti-hepatofibrotic mechanisms upon which quercetin acts have yet to be well characterized. In the present study, we investigated the anti-proliferative effect of quercetin on activated hepatic stellate cells (aHSCs), the central role of hepatofibrosis, and evaluated… CONTINUE READING
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