Antiproliferative effects of daucane esters from Ferula communis and F. arrigonii on human colon cancer cell lines

  title={Antiproliferative effects of daucane esters from Ferula communis and F. arrigonii on human colon cancer cell lines},
  author={F. Poli and G. Appendino and G. Sacchetti and M. Ballero and N. Maggiano and F. Ranelletti},
  journal={Phytotherapy Research},
Certain jaesekanadiol p‐hydroxy‐ and p‐methoxybenzoates – typical of Ferula communis and Ferula arrigonii sardinian plants – show antiproliferative activity on human colon cancer less. The inhibitory doses 50%, calculated after 72 h of treatment, revealed that the antiproliferative capacity of the compounds was in the following descending order: ferutinin > 2α‐OH‐ferutidin > ferutidin > siol anisate > lapiferin > jaeskeanadiol. Evidence is presented that interaction with type II estrogen… Expand
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