Antiproliferative and proapoptotic effects of bisphenol A on human trophoblastic JEG-3 cells.

@article{Morice2011AntiproliferativeAP,
  title={Antiproliferative and proapoptotic effects of bisphenol A on human trophoblastic JEG-3 cells.},
  author={Lucie Morice and Delphine Bena{\^i}treau and Marie-No{\"e}ll{\'e} Dieudonn{\'e} and Corinne Morvan and Val{\'e}rie S{\'e}razin and Philippe de Mazancourt and Ren{\'e} Pecquery and Esther Dos Santos},
  journal={Reproductive toxicology},
  year={2011},
  volume={32 1},
  pages={
          69-76
        }
}
Different studies performed in rodents revealed that bisphenol-A (BPA), an environmental compound, altered early embryonic development. However, little is known concerning the direct effects of BPA on human implantation process. Thus, we decided to study in vitro BPA's effects on proliferative capacities of the human trophoblastic cell line, JEG-3. For this purpose, we first have shown that JEG-3 cells express the specific BPA receptor, namely estrogen-related receptor γ1 (ERRγ1). Secondly, we… CONTINUE READING

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