Antiproliferative activity against human non-small cell lung cancer of two O-alkyl-diglycosylglycerols from the marine sponges Myrmekioderma dendyi and Trikentrion laeve.

@article{Farokhi2012AntiproliferativeAA,
  title={Antiproliferative activity against human non-small cell lung cancer of two O-alkyl-diglycosylglycerols from the marine sponges Myrmekioderma dendyi and Trikentrion laeve.},
  author={Fereshteh Farokhi and Ga{\"e}tane Wielgosz-Collin and Audrey Robic and C{\'e}cile Debitus and Marine Malleter and Christos Roussakis and Jean-Michel Kornprobst and Gilles Barnathan},
  journal={European journal of medicinal chemistry},
  year={2012},
  volume={49},
  pages={406-10}
}
Glycolipids of Myrmekioderma sponges contain Myrmekiosides, a new family of glycolipids with a unique structure of mono-O-alkyl-diglycosylglycerols. This report deals with the identification and biological activity of the new Myrmekioside E from Myrmekioderma dendyi. Its structure has been elucidated from spectroscopic data and chemical degradation studies. It contained a glycerol backbone linked to xylose and N-acetylglucosamine, and an alkyl long-chain with a terminal alcohol group. A related… CONTINUE READING

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