Antiproliferative activities on renal, prostate and melanoma cancer cell lines of Sarcopoterium spinosum aerial parts and its major constituent tormentic acid.

@article{Loizzo2013AntiproliferativeAO,
  title={Antiproliferative activities on renal, prostate and melanoma cancer cell lines of Sarcopoterium spinosum aerial parts and its major constituent tormentic acid.},
  author={M. Loizzo and M. Bonesi and N. G. Passalacqua and Antoine M. Saab and F. Menichini and R. Tundis},
  journal={Anti-cancer agents in medicinal chemistry},
  year={2013},
  volume={13 5},
  pages={
          768-76
        }
}
  • M. Loizzo, M. Bonesi, +3 authors R. Tundis
  • Published 2013
  • Biology, Medicine
  • Anti-cancer agents in medicinal chemistry
  • The search for improved cytotoxic agents continues to be an important line in the discovery of modern anticancer drugs. Sarcopoterium spinosum (L.) Spach is mentioned in ethnobotanical surveys as a medicinal plant used for the treatment of cancer. The aim of this study is to investigate and to compare the aerial parts of S. spinosum collected in Italy and Lebanon for their chemical composition and their antiproliferative activity against ACHN, C32, A375, MCF-7, LNCaP and HeLa human cancer cell… CONTINUE READING
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