[Antiproliferative action of 5'-S-isobutyladenosine in vitro and in vivo on normal and neoplastic mouse cells].

Abstract

Antiproliferative activity of 5'-deoxy-5'-S-isobutylthioadenosine (SIBA) was studied in mouse tumor and medullary cells in vitro and in vivo. Essential differences were found in the antiproliferative action of SIBA on medullary and tumor cells in vivo and in vitro. It was shown that in vitro SIBA drastically inhibited DNA synthesis (by more than 80-90%) in… (More)

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@article{Mironova1984AntiproliferativeAO, title={[Antiproliferative action of 5'-S-isobutyladenosine in vitro and in vivo on normal and neoplastic mouse cells].}, author={S. B. Mironova and M Iu Lidak and Nikolai Andreevich Fedorov and D E Zarinia}, journal={Biulleten' eksperimental'noi biologii i meditsiny}, year={1984}, volume={97 6}, pages={708-10} }