Antiprion immunotherapy: to suppress or to stimulate?

Abstract

Although human prion diseases are rare, they are invariably fatal, and treatments remain elusive. Hundreds of iatrogenic prion transmissions have occurred in the past two decades, and the bovine spongiform encephalopathy epidemic has raised concerns about prion transmission from cattle to humans. Research into therapeutics for prion disease is being pursued… (More)
DOI: 10.1038/nri1437

Topics

7 Figures and Tables