Antiplatelet treatment with ticlopidine in unstable angina. A controlled multicenter clinical trial. The Studio della Ticlopidina nell'Angina Instabile Group.

@article{Balsano1990AntiplateletTW,
  title={Antiplatelet treatment with ticlopidine in unstable angina. A controlled multicenter clinical trial. The Studio della Ticlopidina nell'Angina Instabile Group.},
  author={Francesco Balsano and Paolo Rizzon and Francesco Violi and Domenico Scrutinio and Claudio Cimminiello and Francesco Aguglia and Carlo Pasotti and Giusi Rudelli},
  journal={Circulation},
  year={1990},
  volume={82 1},
  pages={17-26}
}
We conducted a controlled multicenter trial with central randomization and evaluation of events under blind conditions involving 652 patients with unstable angina. Patients were treated either with conventional therapy alone (group C) (n = 338) or with conventional therapy combined with an inhibitor of platelet aggregation, ticlopidine 250 mg b.i.d. (group C + T) (n = 314). Patients were assigned randomly within 48 hours of admission and followed up for 6 months. With the "intention-to-treat… CONTINUE READING

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