Antiplatelet drugs in the secondary prevention after stroke: differential efficacy in large versus small vessel disease? A subgroup analysis from ESPS-2.

@article{Ariesen2006AntiplateletDI,
  title={Antiplatelet drugs in the secondary prevention after stroke: differential efficacy in large versus small vessel disease? A subgroup analysis from ESPS-2.},
  author={M J Ariesen and Ale Algra and L. Jaap Kappelle},
  journal={Stroke},
  year={2006},
  volume={37 1},
  pages={134-8}
}
BACKGROUND AND PURPOSE Arterial disease resulting in cerebral ischemia can be classified into large vessel disease (LVD) and small vessel disease (SVD). We assessed whether antiplatelet drugs were more efficacious in large than in small vessel cerebrovascular disease. METHODS Individual patient data of the second European Stroke Prevention Study (n=6602), in which patients with a previous transient ischemic attack or ischemic stroke were randomized to aspirin, dipyridamole, their combination… CONTINUE READING
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