Antiplatelet agents for preventing pre-eclampsia and its complications.

@article{Duley2004AntiplateletAF,
  title={Antiplatelet agents for preventing pre-eclampsia and its complications.},
  author={Lelia Duley and David J Henderson-smart and Marian Knight and J. Fergus King},
  journal={The Cochrane database of systematic reviews},
  year={2004},
  volume={1},
  pages={
          CD004659
        }
}
BACKGROUND Pre-eclampsia is associated with deficient intravascular production of prostacyclin, a vasodilator, and excessive production of thromboxane, a platelet-derived vasoconstrictor and stimulant of platelet aggregation. These observations led to the hypotheses that antiplatelet agents, low-dose aspirin in particular, might prevent or delay the development of pre-eclampsia. OBJECTIVES To assess the effectiveness and safety of antiplatelet agents when given to women at risk of developing… 
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