Antiplasmodial flavonoids from Erythrina sacleuxii.

@article{Andayi2006AntiplasmodialFF,
  title={Antiplasmodial flavonoids from Erythrina sacleuxii.},
  author={A. Andayi and A. Yenesew and S. Derese and J. Midiwo and P. Gitu and O. J. Jondiko and H. Akala and P. Liyala and Julia M. Wangui and N. Waters and M. Heydenreich and M. Peter},
  journal={Planta medica},
  year={2006},
  volume={72 2},
  pages={
          187-9
        }
}
The acetone extracts of the root bark and stem bark of Erythrina sacleuxii showed antiplasmodial activities against the chloroquine-sensitive (D6) and chloroquine-resistant (W2) strains of Plasmodium falciparum. Chromatographic separation of the acetone extract of the root bark afforded a new isoflavone, 7-hydroxy-4'-methoxy-3'-prenylisoflavone (trivial name 5-deoxy-3'-prenylbiochanin A) along with known isoflavonoids as the antiplasmodial principles. Flavonoids and isoflavonoids isolated from… Expand
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