Antiplasmodial compounds from Cochlospermum tinctorium.

@article{Ballin2002AntiplasmodialCF,
  title={Antiplasmodial compounds from Cochlospermum tinctorium.},
  author={Nicolai Zederkopff Ballin and Maminata Traor{\'e} and Halidou Tinto and Archibald A. Sittie and Per M{\o}lgaard and Carl Erik Olsen and Arsalan Kharazmi and S{\o}ren Br{\o}gger Christensen},
  journal={Journal of natural products},
  year={2002},
  volume={65 9},
  pages={
          1325-7
        }
}
Fractionation of an ethanol extract of roots of Cochlospermum tinctorium afforded five compounds: 3-O-E-p-coumaroylalphitolic acid (1), cochloxanthin (2), dihydrocochloxanthin (3), alphitolic acid (4), and 1-hydroxytetradecan-3-one (5). This is the first example of a 1-hydroxyalkan-3-one obtained from plant material after gentle workup. The antiplasmodial activities of the compounds were determined, and the IC(50) value of 3-O-E-p-coumaroylalphitolic acid was 2.3 microM. 
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Actualités sur les maladies émergentes

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INVESTIGATION OF ANTIPLASMODIAL COMPOUNDS FROM TWO PLANTS, COCHLOSPERMUM TINCTORIUM A

M. Traoréa, A Guiguemdéc, +6 authors T. R. Guiguemdéb
  • 2006
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