Antiplasmodial activity of root extract and fractions of Croton zambesicus.

  title={Antiplasmodial activity of root extract and fractions of Croton zambesicus.},
  author={J. Okokon and P. Nwafor},
  journal={Journal of ethnopharmacology},
  volume={121 1},
  • J. Okokon, P. Nwafor
  • Published 2009
  • Biology, Medicine
  • Journal of ethnopharmacology
  • AIM OF THE STUDY Antiplasmodial activity of root extract and fractions of Croton zambesicus were evaluated to ascertain the folkloric claim of its antimalarial activity and elucidate its antiplasmodial mechanism of action. MATERIAL AND METHOD The crude ethanolic root extract (27-81 mg/kg) and gradient fractions (n- hexane, chloroform, ethyl acetate and methanol; 54 mg/kg) of Croton zambesicus were investigated for antiplasmodial activity against chloroquine--sensitive Plasmodium berghei… CONTINUE READING
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