Antiplasmodial activity of a series of 1,3,5-triazine-substituted polyamines.

Abstract

Polyamine biosynthesis and function has been shown to be a good drug target in some parasitic protozoa and it is proposed that the pathway might also represent a target in the malaria parasite Plasmodium falciparum. A series of 1,3,5-triazine-substituted polyamine analogues were tested for activity against Plasmodium falciparum in vitro. The series showed… (More)

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@article{Klenke2003AntiplasmodialAO, title={Antiplasmodial activity of a series of 1,3,5-triazine-substituted polyamines.}, author={Burkhard Klenke and Michael P. Barrett and Reto Brun and Ian H. Gilbert}, journal={The Journal of antimicrobial chemotherapy}, year={2003}, volume={52 2}, pages={290-3} }