Antiphotoaging effect of chitooligosaccharides on human dermal fibroblasts.

BACKGROUND/PURPOSE In the present study, the effect of 3-5 kDa chitooligosaccharide (COS) on homeostasis between the expression of collagen-degrading matrix metalloproteinases (MMPs) and collagen synthesis was investigated using ultraviolet (UV)-A irradiated dermal fibroblasts. METHODS UV protection imparted by 3-5 kDa COS was measured by examining the UV… (More)