Antiphospohlipid syndrome in obstetrics.

  title={Antiphospohlipid syndrome in obstetrics.},
  author={Alvaro Danza and Guillermo Ruiz-Irastorza and Munther A. Khamashta},
  journal={Best practice & research. Clinical obstetrics & gynaecology},
  volume={26 1},
Antiphospholipid syndrome is characterised by a variety of clinical and immunological manifestations. The clinical hallmarks of this syndrome are thrombosis and poor obstetric outcomes, including miscarriages, fetal loss and severe pre-eclampsia. The main antiphospholipid antibodies include lupus anticoagulant, anticardiolipin and anti-β2-glycoprotein I. The combination of aspirin and heparin is considered the standard of care for women with antiphospholipid syndrome and embryo-fetal losses… CONTINUE READING