[Antiphospholipid syndrome].

Abstract

Antiphospholipid syndrome is a well-defined clinical and serological entity characterized by arterial and/or venous thrombosis, recurrent abortion and thrombocytopenia. Anticardiolipin antibodies and lupus anticoagulant are autoantibodies directed against negatively charged phospholipids, which represent the serologic criteria for the diagnosis of the antiphospholipid syndrome. In this review the pathogenic mechanisms of anticardiolipin antibodies, their clinical findings and the current therapeutical strategies are discussed.

Cite this paper

@article{Yuste1998AntiphospholipidS, title={[Antiphospholipid syndrome].}, author={Jose R Yuste and Oscar Beloqui and Andr{\'e}s de la Pe{\~n}a and Jos{\'e} Pedro Prieto}, journal={Revista de medicina de la Universidad de Navarra}, year={1998}, volume={42 4}, pages={194-207} }