Antiphospholipid antibodies in blood and cerebrospinal fluids of patients with psychosis

@article{Sokol2007AntiphospholipidAI,
  title={Antiphospholipid antibodies in blood and cerebrospinal fluids of patients with psychosis},
  author={D. Sokol and Roderick S. O'Brien and D. Wagenknecht and T. Rao and J. Mcintyre},
  journal={Journal of Neuroimmunology},
  year={2007},
  volume={190},
  pages={151-156}
}
Antiphospholipid antibodies (aPL) have been reported in the cerebrospinal fluids (CSF) of neurology patients but no CSF studies with psychiatric patients exist. We tested serum from 100 hospitalized psychotic patients having hallucinations and/or delusions for aPL. Patients with positive serum aPL findings were asked to submit CSF for aPL testing. Five CSF samples had aPL specificities not found in the patient's serum suggesting the possibility of intrathecal synthesis. Specificity and isotype… Expand
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