Antiphospholipid antibodies and subsequent thrombo-occlusive events in patients with ischemic stroke.

@article{Levine2004AntiphospholipidAA,
  title={Antiphospholipid antibodies and subsequent thrombo-occlusive events in patients with ischemic stroke.},
  author={S. R. Levine and Robin L. Brey and Barbara C. Tilley and John L. P. Thompson and Ralph L. Sacco and Robert R. Sciacca and Amy B. Murphy and Yimeng Lu and Teresa M Costigan and Candi Rhine and Bruce Levin and Douglas A. Triplett and Jay P. Mohr},
  journal={JAMA},
  year={2004},
  volume={291 5},
  pages={576-84}
}
CONTEXT The presence of antiphospholipid antibodies (aPL) has been associated with vascular occlusive events. However, the role of aPL in predicting ischemic events, particularly recurrent ischemic stroke, is controversial. OBJECTIVE To evaluate the effect of baseline aPL positivity (ie, positivity for anticardiolipin antibodies [aCL], lupus anticoagulant antibodies [LA], or both) on subsequent thrombo-occlusive events, including recurrent stroke. DESIGN, SETTING, AND PARTICIPANTS The… CONTINUE READING