Antiperspirants and the hyperhidrosis patient

  title={Antiperspirants and the hyperhidrosis patient},
  author={Zoe Diana Draelos},
  journal={Dermatologic Therapy},
  • Z. Draelos
  • Published 2001
  • Medicine
  • Dermatologic Therapy
Hyperhidrosis is the production of excess sweat of the armpits, hands, feet, or face. The sweating can be simply unsightly or a true impairment to the optimal functioning of children and adults. This dermatologic problem can be treated with topical antiperspirants, oral medications, or by injections of botulinum toxin. This article examines the physiology of sweat reduction and the efficacy of various therapies, and presents a practical approach for the treatment of this condition. 
Botulinum Toxin for Hyperhidrosis
Recent evidence suggests that botulinum toxin type A (BTX-A) injections into hyperhidrotic areas can considerably reduce focal sweating in multiple areas without major adverse effects, and BTx-A has therefore shown promise as a potential replacement for more invasive treatments after topical aluminum salts have failed. Expand
nguinal , or Hexsel ’ s Hyperhidrosis ÓRIS
Inguinal Hyperhidrosis (IH) is a focal and primary form of hyperhidrosis in which the individual has intense sweating in the inguinal region. It usually appears in adolescence, not later than the ageExpand
Inguinal, or Hexsel's hyperhidrosis.
Intradermal injections from botulinum toxin provide positive results for the patients and controls the sweating for 6 months or more and significantly improve the quality of life of the affected individuals. Expand
The Etiology, Diagnosis and Management of Hyperhidrosis: A Comprehensive Review. Part II. Therapeutic Options.
A review of treatment modalities for HH and a sequenced approach are presented and Iontophoresis is considered to be the primary remedy for palmar and plantar HH. Expand
Hyperhidrosis: A Review of a Medical Condition
To understand the disorder of hyperhidrosis, it is necessary to explore the biology of sweat glands including the eccrine, apocrine, and apoeccrine sweat glands. Expand
Antiperspirantien bei der Behandlung der fokalen Hyperhidrose
Antiperspirantien werden als kosmetische Mittel definiert, die die Schweißbildung durch das Beeinflussen der ekkrinen -Schweißdrüsen reduzieren 18.000 sterben, wird insbesondere in Deutschland der Begriff „Deo“ als Überbegriff verwendet. Expand
Antiperspirantien bei der Behandlung der fokalen Hyperhidrose
Rare variants of focal hyperhidrosis like auriculotemporal syndrome, Ross syndrome and nevus sudoriferus also are suitable for treatment with topical aluminum chloride hexahydrate solutions. Expand
Most US consumers use an antiperspirant/deodorant (AP/DEO) daily to reduce underarm perspiration and odor. Female consumers have expressed interest in an AP/DEO that will reduce the appearance ofExpand
Assessment of Dermal Absorption of Aluminum from a Representative Antiperspirant Formulation Using a 26Al Microtracer Approach
A clinical pharmacokinetic study was performed in 12 healthy women to evaluate systemic exposure to aluminum following topical application of a representative antiperspirant formulation underExpand
Use of short-chain glycols as antitranspirantwirksame means
Verwendung von kurzkettigen vicinalen Diolen mit einer C-Atomanzahl von 2 bis 4 als schweishemmende Wirkstoffe in einer Konzentration von 15 bis 50 Gew.-%.


Mechanisms of eccrine anidrosis. II. The antiperspirant effect of aluminum salts.
Studies on topical antiperspirant control of axillary hyperhidrosis.
The hypothesis is presented that metallic antiperspirants act by reflux entrance into the terminal intraepidermal eccrine duct, slowly combining with the intraductal keratin, to produce a fibrillar contraction (super contraction) of keratin and hence functional closure, not histologically evident. Expand
Antiperspirants and deodorants.
The physiology of human perspiration is reviewed and the function and classification of antiperspirants and deodorants are described. Expand
The mechanism of antiperspirant action in eccrine sweat glands
  • Antiperspirants and Deodorants
  • 1988
Rationale of formulations of deodorants and antiperspirants
  • 1982
Mechanisms of eccrine anhidrosis: II. The antiperspirant effects of aluminium salts
  • J Invest Dermatol
  • 1967