Antiperoxidative effects of lycopene during N-methyl-N'-nitro-N-nitrosoguanidine-induced gastric carcinogenesis.
@article{Velmurugan2002AntiperoxidativeEO, title={Antiperoxidative effects of lycopene during N-methyl-N'-nitro-N-nitrosoguanidine-induced gastric carcinogenesis.}, author={B. Velmurugan and V. Bhuvaneswari and S. Nagini}, journal={Fitoterapia}, year={2002}, volume={73 7-8}, pages={ 604-11 } }
The effects of lycopene on blood oxidant-antioxidant balance during N-methyl-N'-nitro-N-nitrosoguanidine (MNNG)-induced gastric carcinogenesis in the presence of saturated sodium chloride (S-NaCl) as promoting agent were investigated. Enhanced lipid peroxidation in the blood of tumour-bearing animals was accompanied by significant decreases in the levels of reduced glutathione (GSH), ascorbic acid and vitamin E and the activities of glutathione peroxidase (GPx), glutathione-S-transferase (GST… CONTINUE READING
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