Antioxidative and therapeutic effects of spirulina on trichloroethylene induced cutaneous irritation balb/c mice.

@article{Gurbuz2013AntioxidativeAT,
  title={Antioxidative and therapeutic effects of spirulina on trichloroethylene induced cutaneous irritation balb/c mice.},
  author={Neslihan Gurbuz and Zafer Kutay Coşkun and Suna Omeroğlu and A C Bayraktar and Zahid Çiraci},
  journal={Bratislavske lekarske listy},
  year={2013},
  volume={114 4},
  pages={
          192-8
        }
}
OBJECTIVES To evaluate the antioxidative and therapeutic effects of spirulina on the trichloroethylene induced cutaneous irritation balb/c mice. BACKGROUND During recent years, an attention has been focused on the antioxidant potential of Spirulina species. METHODS Balb/c mice were randomized into the four groups. At the end of the each application, the rats were sacrificed and dorsal skin was taken. Histopathologic and immunohistochemical evaluations were conducted, oxidative stress was… Expand
The antioxidant, immunomodulatory, and anti-inflammatory activities of Spirulina: an overview
TLDR
Clinical trials show that Spirulina prevents skeletal muscle damage under conditions of exercise-induced oxidative stress and can stimulate the production of antibodies and up- or downregulate the expression of cytokine-encoding genes to induce immunomodulatory and anti-inflammatory responses. Expand
Revealing the potential of cyanobacteria in cosmetics and cosmeceuticals — A new bioactive approach
TLDR
A general overview of the state of the art regarding the potential of cyanobacteria for the cosmetic and cosmeceutical industry is provided, emphasizing the main properties required in skin care formulations. Expand

References

SHOWING 1-10 OF 32 REFERENCES
Trichloroethylene induced cutaneous irritation in BALB/c hairless mice: histopathological changes and oxidative damage.
TLDR
The results suggest that TCE is capable of producing skin irritation effect in vivo, with histopathological changes characterized by hyperkeratosis, spongiosis and inflammatory cell infiltrates in TCE-induced skin irritation. Expand
Protective Effects of Pine Bark Extract on Hexavalent Chromium‐Induced Dermatotoxicity in Rats
TLDR
PBE has a protective effect against Cr( VI)‐induced dermatotoxicity and is useful as a protective agent against various dermal lesions induced by oxidative stress, and concomitant administration with PBE effectively prevents Cr(VI)‐ induced oxidative damage in rats. Expand
Preventive effects of Spirulina platensis on skeletal muscle damage under exercise-induced oxidative stress
TLDR
The results suggest that ingestion of S. platensis showed preventive effect of the skeletal muscle damage and that probably led to postponement of the time of exhaustion during the all-out exercise. Expand
[Changes of nitric oxide after trichloroethylene irritation in hairless mice skin and protection of ginkgo biloba extract and vitamin E].
TLDR
TCE can produce the irritation on the dorsal skin of BALB/c hairless mice and induce the significant increase of the NO levels and GbE and VE can protect the skin from TCE irritation damage. Expand
Effect of Spirulina, a blue green algae, on gentamicin‐induced oxidative stress and renal dysfunction in rats
TLDR
The results of present study clearly demonstrate the pivotal role of reactive oxygen species and their relation to renal dysfunction and point to the therapeutic potential of S. fusiformis in GM‐induced nephrotoxicity. Expand
Protection against cisplatin-induced nephrotoxicity by Spirulina in rats
TLDR
In vitro studies using human ovarian cancer cells revealed that Spirulina did not interfere with the cytotoxic effects of CP on tumor cells, and protected the rats from CP-induced nephrotoxicity through its antioxidant properties. Expand
Protective effect of Spirulina on lead induced deleterious changes in the lipid peroxidation and endogenous antioxidants in rats
TLDR
Although, Spirulina did not affect the deposition of lead in organs apart from the brain, simultaneous administration of Spiruline to lead exposed animals inhibited lipid peroxidation and restored the levels of endogenous antioxidants to normal. Expand
Renoprotective Effect of Spirulina fusiformis on Cisplatin-Induced Oxidative Stress and Renal Dysfunction in Rats
TLDR
The results of the present study clearly demonstrate the pivotal role of reactive oxygen species and their relation to renal dysfunction and point to the therapeutic potential of Spirulina fusiformis in cisplatin-induced nephrotoxicity. Expand
Nutritional and therapeutic potential of Spirulina.
TLDR
Spirulina have been found to be active against several enveloped viruses including herpes virus, cytomegalovirus, influenza virus and HIV, capable to inhibit carcinogenesis due to anti-oxidant properties that protect tissues and also reduce toxicity of liver, kidney and testes. Expand
A subchronic exposure to trichloroethylene causes lipid peroxidation and hepatocellular proliferation in male B6C3F1 mouse liver.
TLDR
The temporal relationship between oxidative stress and cellular response of proliferation, both of which occur and resolve within the same relative time period, suggests that TCE-induced mitogenesis may result from alteration in the liver microenvironment which offers a selective advantage for certain hepatocyte subpopulations. Expand
...
1
2
3
4
...