Antioxidants decreases the intensification of low density lipoprotein in vivo peroxidation during therapy with statins

@article{Lankin2004AntioxidantsDT,
  title={Antioxidants decreases the intensification of low density lipoprotein in vivo peroxidation during therapy with statins},
  author={Vadim Z. Lankin and Alla K. Tikhaze and Valery V. Kukharchuk and Galina G. Konovalova and Oleg Pisarenko and Alexander I. Kaminnyi and Konstantin B Shumaev and Yu. N. Belenkov},
  journal={Molecular and Cellular Biochemistry},
  year={2004},
  volume={249},
  pages={129-140}
}
The oxidative modification of low density lipoprotein (LDL) is thought to play an important role in atherogenesis. Drugs of β-hydroxy-β-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors (statins) family are usually used as a very effective lipid-lowering preparations but they simultaneously block biosynthesis of both cholesterol and ubiquinone Q10 (coenzyme Q), which is an intermediate electron carrier in the mitochondrial respiratory chain. It is known that reduced form of ubiquinone… 
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