Antioxidants and neuroprotection in the adult and developing central nervous system.

  title={Antioxidants and neuroprotection in the adult and developing central nervous system.},
  author={C. Kaur and E. Ling},
  journal={Current medicinal chemistry},
  volume={15 29},
Oxidative stress is implicated in the pathogenesis of a number of neurological disorders such as Alzheimer's disease (AD), Parkinson's disease (PD), multiple sclerosis and stroke in the adult as well as in conditions such as periventricular white matter damage in the neonatal brain. It has also been linked to the disruption of blood brain barrier (BBB) in hypoxic-ischemic injury. Both experimental and clinical results have shown that antioxidants such as melatonin, a neurohormone synthesized… Expand
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