Antioxidant vitamins intake, ataxia telangiectasia mutated (ATM) genetic polymorphisms, and breast cancer risk.

@article{Lee2010AntioxidantVI,
  title={Antioxidant vitamins intake, ataxia telangiectasia mutated (ATM) genetic polymorphisms, and breast cancer risk.},
  author={Sang-Ah Lee and Kyoung-Mu Lee and Seung-Joon Lee and Keun-young Yoo and Sue Kyung Park and Dong-Young Noh and Sei-hyun Ahn and Daehee Kang},
  journal={Nutrition and cancer},
  year={2010},
  volume={62 8},
  pages={1087-94}
}
Ataxia telangiectasia mutated (ATM) cells exist under a constant state of oxidative stress with high levels of reactive oxygen species, which are removed by cellular antioxidant vitamins. We investigated the independent and combined effect of antioxidant vitamins intake and the ATM genotype or diplotype on the breast cancer risk. Analyses included 323 cases and age-matched controls who participated in the Korean Breast Cancer Study during 2001-2003 with complete dietary information. The vitamin… CONTINUE READING