Antioxidant vitamins C and E improve endothelial function in children with hyperlipidemia: Endothelial Assessment of Risk from Lipids in Youth (EARLY) Trial.

@article{Engler2003AntioxidantVC,
  title={Antioxidant vitamins C and E improve endothelial function in children with hyperlipidemia: Endothelial Assessment of Risk from Lipids in Youth (EARLY) Trial.},
  author={Marguerite M. Engler and Mary B. Engler and Mary J. Malloy and Elisa Y Chiu and Monique C Schloetter and Steven M Paul and Markus Stuehlinger and Ken Y Lin and John P Cooke and Jason D. Morrow and Paul M. Ridker and Nader Rifai and Elizabeth Miller and Joseph L. Witztum and Michele L. Mietus-Snyder},
  journal={Circulation},
  year={2003},
  volume={108 9},
  pages={1059-63}
}
BACKGROUND Hyperlipidemia is associated with endothelial dysfunction, an early event in atherosclerosis and predictor of risk for future coronary artery disease. Epidemiological studies suggest that increased dietary intake of antioxidants reduces the risk of coronary artery disease. The purpose of this study was to determine whether antioxidant vitamin therapy improves endothelial function and affects surrogate biomarkers for oxidative stress and inflammation in hyperlipidemic children… CONTINUE READING
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