Antioxidant therapy in Parkinson's disease.

Abstract

It is postulated that endogenous oxidative mechanisms are a major factor in the continuing death of dopaminergic neurons and the progression of Parkinson's disease. Scientific evidence in support of, and negating, the free radical auto-toxicity and dopamine toxicity concepts is reviewed. There is conflicting evidence whether free radicals are involved in… (More)

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@article{Grimes1987AntioxidantTI, title={Antioxidant therapy in Parkinson's disease.}, author={Jonathan Grimes and Marwa Hassan and Juilee Thakar}, journal={The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques}, year={1987}, volume={14 3 Suppl}, pages={483-7} }