Antioxidant systems in rat lens as a function of age: effect of chronic administration of vitamin E and ascorbate.

@article{Campisi1999AntioxidantSI,
  title={Antioxidant systems in rat lens as a function of age: effect of chronic administration of vitamin E and ascorbate.},
  author={Agata Campisi and Claudia Di Giacomo and Alessandro Russo and Valeria Sorrenti and G. Vanella and Rosaria Acquaviva and Giovanni Li Volti and Angelo Vanella},
  journal={Aging},
  year={1999},
  volume={11 1},
  pages={39-43}
}
Oxidative damage occurring in the lenses of patients with senile cataract may be due to partially reduced forms of oxygen. We assayed the activities of superoxide dismutase (SOD), glutathione peroxidase (GSH-Px), glutathione reductase (GSH-Red), and glucose-6-phosphate dehydrogenase (G6PD) in rat lenses at different ages (1, 4, and 24 months), and also evaluated lens glutathione (GSH) levels and the effects of chronic administration of vitamin E and sodium ascorbate. We observed a significant… CONTINUE READING