Antioxidant strategies in respiratory medicine.

  title={Antioxidant strategies in respiratory medicine.},
  author={Melpo Christofidou-Solomidou and Vladimir R Muzykantov},
  journal={Treatments in respiratory medicine},
  volume={5 1},
Pulmonary oxidant stress plays an important pathogenetic role in disease conditions including acute lung injury/adult respiratory distress syndrome (ALI/ARDS), hyperoxia, ischemia-reperfusion, sepsis, radiation injury, lung transplantation, COPD, and inflammation. Reactive oxygen species (ROS), released from activated macrophages and leukocytes or formed in the pulmonary epithelial and endothelial cells, damage the lungs and initiate cascades of pro-inflammatory reactions propagating pulmonary… CONTINUE READING
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