Antioxidant status in patients with uncomplicated insulin‐dependent and non‐insulin‐dependent diabetes mellitus

@article{Maxwell1997AntioxidantSI,
  title={Antioxidant status in patients with uncomplicated insulin‐dependent and non‐insulin‐dependent diabetes mellitus},
  author={S. R. J. Maxwell and Helen Thomason and D Sandler and Ca Leguen and M. A. Baxter and Ghg Thorpe and A. F. Jones and Anthony H. Barnett},
  journal={European Journal of Clinical Investigation},
  year={1997},
  volume={27}
}
Oxidative damage by free radicals has been implicated in the pathogenesis of vascular disease in diabetes. We compared the radical‐scavenging antioxidant activity of serum from 28 patients with insulin‐dependent diabetes mellitus and 24 patients with non‐insulin‐dependent diabetes mellitus uncomplicated by vascular disease with age‐matched non‐diabetic control subjects. Patients with insulin‐dependent diabetes had significantly reduced total antioxidant activity (320.2 ± 11.3 vs. 427.5 ± 19.2… 
Poor Glycaemic Control is Associated with Reduced Serum Free Radical Scavenging (Antioxidant) Activity in Non-Insulin-Dependent Diabetes Mellitus
TLDR
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