Antioxidant responsiveness in BALB/c mice exposed to ozone.

  title={Antioxidant responsiveness in BALB/c mice exposed to ozone.},
  author={An Soo Jang and Inseon S. Choi and Sung-Yeul Yang and Young-Gon Kim and June-Hyuk Lee and Sung-Woo Park and Choon-Sik Park},
  journal={Respiration; international review of thoracic diseases},
  volume={72 1},
BACKGROUND A single, acute exposure to ozone has been shown to modify the antioxidant defense mechanism in the respiratory tract. OBJECTIVE The aim of this study was to evaluate the effects of ozone exposure on antioxidant response in BALB/c mice. METHODS We measured enhanced pause of breathing (Penh) as a marker of airway obstruction using barometric whole-body plethysmography before and after ozone exposure [groups (n = 6): filtered air, 0.12 ppm, 0.5 ppm, 1 ppm, 2 ppm] for 3 h… CONTINUE READING


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