Antioxidant response and oxidative damage in brain cortex after high dose of pilocarpine

@article{Tejada2007AntioxidantRA,
  title={Antioxidant response and oxidative damage in brain cortex after high dose of pilocarpine},
  author={S. Tejada and A. Sureda and C. Roca and A. Gamundi and S. Esteban},
  journal={Brain Research Bulletin},
  year={2007},
  volume={71},
  pages={372-375}
}
Pilocarpine is a cholinergic agonist capable to induce seizures and an epilepticus-like state in rodents. This status epilepticus (SE) is an useful animal model to study the development and understanding of the neuropathology, behavioural and electroencephalographic alterations of human temporal lobe epilepsy. It has been suggested a relationship between SE and reactive oxygen species (ROS) that can result in seizure-induced neurodegeneration. The aim of this study was to evaluate the existence… Expand
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