Antioxidant properties of 4-methylcoumarins in in vitro cell-free systems.


4-methylcoumarins that possess two hydroxyl groups ortho to each other in the benzenoid ring have shown to have excellent antioxidant and radical-scavenging properties in different experimental models. Furthermore, they cannot be metabolized by the liver P450 monoxygenases and thus cannot form 3,4-coumarin epoxides, which are believed to be mutagenic… (More)
DOI: 10.1016/j.biochi.2010.04.017


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