• Corpus ID: 6373065

Antioxidant potential of Aesculus hippocastanum extract and escin against reactive oxygen and nitrogen species.

@article{Vakov2015AntioxidantPO,
  title={Antioxidant potential of Aesculus hippocastanum extract and escin against reactive oxygen and nitrogen species.},
  author={Janka Va{\vs}kov{\'a} and Andrea Fejer{\vc}{\'a}kov{\'a} and Gabriela Moj{\vz}i{\vs}ov{\'a} and Ladislav Va{\vs}ko and Peter Patlevi{\vc}},
  journal={European review for medical and pharmacological sciences},
  year={2015},
  volume={19 5},
  pages={
          879-86
        }
}
OBJECTIVE Antioxidant, anti-inflammatory and venoconstrictor properties have been attributed to extracts from Aesculus hippocastanum. These unusual and diverse properties may be possibly basically linked with ability to scavenge free radicals. MATERIALS AND METHODS The scavenging capacity of dry horse chestnut extract of and escin have been investigated in vitro against superoxide anion radicals, hydroxyl radicals, nitrites and peroxynitrite. RESULTS In general, the activity of the whole… 

Figures from this paper

Antimicrobial Activity, Antioxidant Properties and Phytochemical Screening of Aesculus hippocastanum Mother Tincture against Food-borne Bacteria

The synergistic actions of bioactive compounds detected in the TM might be on the basis of the antioxidant and biological activities observed and can be applied in the pharmaceutical field and also in food preservation, alternative medicine and natural therapies.

Enzyme and Biological Activities of the Water Extracts from the Plants Aesculus hippocastanum, Olea europaea and Hypericum perforatum That Are Used as Folk Remedies in Turkey

The phytochemical contents of the water extracts from three different plants used as folk remedies in Turkey are compared to confirm that A. hippocastanum, O. europaea, and H. perforatum represent a potential source of natural-derived molecules with positive properties that could be used as valid starting point for new food supplements, and drugs in the pharmaceutical, cosmetic, and food industries.

The Protective Effect of Aesculus hippocastanum (Venoplant®) Against Concanavalin A-Induced Liver Injury

AH (Venoplant®) could significantly protect the ConA-induced acute liver injury in mice via inhibition of reactive oxygen species and JNK pathway.

Sustainable Extraction and Characterisation of Bioactive Compounds from Horse Chestnut Seed Coats for the Development of Bio-Based Additives

Background: To protect renewable packaging materials against autoxidation and decomposition when substituting harmful synthetic stabilizers with bioactive and bio-based compounds, extracts from

ANTIMICROBIAL AND ANTIOXIDANT PROPERTIES AND PHYTOCHEMICAL SCREENING OF DIFFERENT MOTHER TINCTURES AGAINST FOOD-BORNE BACTERIA

The observed antimicrobial and antioxidant activities might be due to the synergistic actions of bioactive compounds detected in the mother tinctures and could be applied in pharmaceutical field, establishing an important role of mother tarentures in phytotherapy and also in food preservation, alternative medicine and natural therapies.

Biological properties of Cakile maritima Scop. (Brassicaceae) extracts.

The study suggests that CKM possesses antioxidant, anti-inflammatory, antibacterial, anti -proliferative activities and such pleiotropic effects may be exploited under various pathological conditions.

Assessment of β-Aescin Effect in Streptozotocin Induced Diabetic Model: Diabetic Hepatotoxicity Study

Histopathological evaluation showed severe changes in untreated diabetic liver tissue marked by large number of inflammatory cells such as lymphocytes along with hepatic sinusoidal inflammation and hepatocyte necrosis whereas treated diabetic mice with βaescin showed reduction in hepatotoxicity marked by regeneration changes of hepatocytes and mildly hepatocyte degeneration.

New natural barrigenol-like triterpenoid isolated from the husks of Xanthoceras sorbifolia Bunge

The present study has led to the purification of a new triterpenoid saponin, 21β-O-acetyl-xanthohuskiside A, together with six known barrigenol derivatives, whose structures were authenticated on the basis of NMR, HR-MS, IR spectrum and acid hydrolysis experiment.

Aesculus hippocastanum L. Extract Does Not Induce Fibroblast to Myofibroblast Conversion but Increases Extracellular Matrix Production In Vitro Leading to Increased Wound Tensile Strength in Rats

The direct comparison of both basic wound models demonstrated that the healing was significantly increased following HCE, thus this extract may be found useful to improve healing of acute wounds.

References

SHOWING 1-10 OF 25 REFERENCES

Characterisation of the antioxidant effects of Aesculus hippocastanum L. bark extract on the basis of radical scavenging activity, the chemiluminescence of human neutrophil bursts and lipoperoxidation assay.

These findings are interesting for improving the antioxidant network and restoring redox balance in human cells, and extend the possibility of using plant-derived molecules to antagonise the oxidative stress generated in living organisms when the balance is in favour of free radicals as a result of the depletion of cell antioxidants.

Total phenolic content and antioxidant activity of ethanolic extracts of Aesculus hippocastanum L.

e Abstract: Aesculus hippocastanum L. (horse chestnut) belongs to the genus Aesculus, the most widespread genus of the Hippocastanaceae family, and it is native to the countries of the Balkan

Structural aspects of antioxidant activity of flavonoids.

Active-oxygen scavenging activity of plant extracts.

Both Aeseclus hippocastanum L. and Hamamelis virginiana L. were found to have strong active-oxygen scavenging activity of and protective activity against cell damage induced by active oxygen.

Antioxidant and Antiradical Properties of Esculin, and its Effect in A Model of Epirubicin-Induced Bone Marrow Toxicity

The ability of the coumarin glucoside esculin to scavenge superoxide radicals and to decrease Fe-induced lipid peroxidation was documented, however, despite the registered antioxidant effects the tested compound failed to exert cytoprotection in models of anthracycline-induced genotoxicity in bone marrow cells.

Aescin: pharmacology, pharmacokinetics and therapeutic profile.

  • C. Sirtori
  • Medicine, Biology
    Pharmacological research
  • 2001
The excellent tolerability of aescin in the clinic indicates this treatment is of definite clinical benefit in patients with clinical conditions resulting in chronic venous insufficiency, haemorrhoids or peripheral oedema formation.

Horse Chestnut (Aesculus hippocastanum L.)

Mainly three effects of horse chestnut extract on CVI can be identified: anti-oedomatous, anti-inflammatory and venotonic.