Antioxidant enzymes in cerebral cortex of immature rats following experimentally-induced seizures: upregulation of mitochondrial MnSOD (SOD2)

@article{Folbergrov2013AntioxidantEI,
  title={Antioxidant enzymes in cerebral cortex of immature rats following experimentally-induced seizures: upregulation of mitochondrial MnSOD (SOD2)},
  author={Jaroslava Folbergrov{\'a} and Pavel Je{\vs}ina and Hana Nůskov{\'a} and Josef Hou{\vs}těk},
  journal={International Journal of Developmental Neuroscience},
  year={2013},
  volume={31},
  pages={123-130}
}
We have recently demonstrated the evidence of oxidative stress in brain of immature rats during seizures induced by DL-homocysteic acid (DL-HCA). The aim of the present study was to investigate the antioxidant defense mechanisms under these conditions. Seizures were induced in immature 12-day-old rats by bilateral icv infusion of DL-HCA (600 nmol/side), and the activities of the main antioxidant enzymes were examined in supernatants of the cerebral cortex during the acute phase of seizures and… CONTINUE READING
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