Antioxidant enzyme deficiencies and vascular disease.

  • Joseph Loscalzo
  • Published 2010 in Expert review of endocrinology & metabolism


Cellular respiration in an oxygen-rich environment leads to the generation of reactive oxygen species. These partially reduced forms of molecular oxygen can readily react with biological molecules, often modifying their normal biological function. Antioxidant enzyme mechanisms have evolved to eliminate reactive oxygen species and minimize the oxidant stress… (More)


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