Antioxidant effects of a grapeseed procyanidin extract and oleoyl-estrone in obese Zucker rats.

@article{Castrillejo2011AntioxidantEO,
  title={Antioxidant effects of a grapeseed procyanidin extract and oleoyl-estrone in obese Zucker rats.},
  author={Vanessa M Castrillejo and Miguel Romero and Montserrat Esteve and Anna Ard{\'e}vol and M Teresa Blay and Cinta Blad{\'e} and Luis Arola and M Josepa Salvad{\'o}},
  journal={Nutrition},
  year={2011},
  volume={27 11-12},
  pages={1172-6}
}
OBJECTIVE To substantiate the relation between obesity and oxidative stress and to assess the potential beneficial properties of a grapeseed proanthocyanidin extract (GSPE), the amelioration of obesity with oleoyl-estrone (OE), and the possible combined effect of GSPE and OE on the hepatic and renal antioxidant enzyme system in obesity-induced oxidative stress. METHODS Male obese Zucker rats were divided into four groups: GSPE, OE, GSPE + OE, and OC (control). For 30 d they were gavaged with… CONTINUE READING

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