Antioxidant effect of taurine against lead-induced oxidative stress.

  title={Antioxidant effect of taurine against lead-induced oxidative stress.},
  author={H G{\"u}rer and Hilal Ozg{\"u}neş and Erdinc Saygin and Nuran Ercal},
  journal={Archives of environmental contamination and toxicology},
  volume={41 4},
Oxidative stress is proposed as a molecular mechanism in lead toxicity, which suggests that antioxidants might play a role in the treatment of lead poisoning. The present study was designed to investigate whether taurine has a beneficial effect both on Chinese hamster ovary (CHO) cells and on Fisher 344 (F344) rats following lead exposure. Therefore, oxidative stress parameters (glutathione, malondialdehyde levels, catalase, and glucose-6-phosphate dehydrogenase [G6PD] activities) of lead… CONTINUE READING