Antioxidant effect of astaxanthin on phospholipid peroxidation in human erythrocytes.

@article{Nakagawa2011AntioxidantEO,
  title={Antioxidant effect of astaxanthin on phospholipid peroxidation in human erythrocytes.},
  author={Kiyotaka Nakagawa and Takehiro Kiko and Teruo Miyazawa and Gregor Carpentero Burdeos and Fumiko Kimura and Akira Satoh},
  journal={The British journal of nutrition},
  year={2011},
  volume={105 11},
  pages={1563-71}
}
Phospholipid hydroperoxides (PLOOH) accumulate abnormally in the erythrocytes of dementia patients, and dietary xanthophylls (polar carotenoids such as astaxanthin) are hypothesised to prevent the accumulation. In the present study, we conducted a randomised, double-blind, placebo-controlled human trial to assess the efficacy of 12-week astaxanthin supplementation (6 or 12 mg/d) on both astaxanthin and PLOOH levels in the erythrocytes of thirty middle-aged and senior subjects. After 12 weeks of… CONTINUE READING