Antioxidant compound Quercetin-3-O-α-L-rhamnoside (1→6)-β-D-glucose (Rutin) isolated from ethyl acetate leaf extracts of Memecylon edule Roxb (Melastamataceae)

  title={Antioxidant compound Quercetin-3-O-$\alpha$-L-rhamnoside (1→6)-$\beta$-D-glucose (Rutin) isolated from ethyl acetate leaf extracts of Memecylon edule Roxb (Melastamataceae)},
  author={Ramalingam Srinivasan and Devarajan Natarajan and Muthugounder Subramanian Shivakumar},
  journal={Free Radicals and Antioxidants},
Introduction: The present study was aimed to isolate antioxidant principle from leaf ethyl acetate extract of Memecylon edule for the first time. M. edule belongs to melastomataceae family; possess various biological properties and folklore uses. Methods: Isolation of antioxidant compound was carried out by DPPH radicals scavenging activity guided method and employing chromatography techniques (TLC and column chromatography). The structure of isolated bioactive compound (Rutin) was confirmed by… 

Figures and Tables from this paper

In vitro evaluation of antioxidant, antiproliferative potentials of bioactive extract-cum-rutin compound Isolated from Memecylon edule leaves and its molecular docking study

Abstract The current study was planned to investigate the antioxidant and anti-proliferative potential of leaf crude extracts and isolated compound (rutin) from Memecylon edule by performing the

Chemical Constituents , Antioxidant , Antimicrobial and Anti-inflammatory Activities of Erysimum corinthium Boiss . ( Brassicaceae )

Aerial part of Erysimum corinthium Boiss (Brassicaceae) was subjected to chromatographic and biological investigations. GLC analysis of fatty acids methyl esters revealed the presence of 13 fatty

Isolation of a new compound, 2-butanone 4-glucopyranoside 6′-O-gallate and other 8 compounds from the anti-inflammatory leave extracts of Memecylon edule Roxb

M. edule was recognised to be a good source for phenolic compounds and these compounds may contribute to anti-inflammatory activity of the extract.

Phytochemical and Biological Investigation of Thunbergia grandiflora

Aqueous methanol extract of Thunbergia grandiflora Roxb leaves exhibited marked hypoglycemic activity comparable to metformin as reference drug and antioxidant activity that was evaluated by glutathione and DPPH radical scavenging activity methods in comparison with vitamin E, as well as hepatoprotective effect to liver damaged rats using CCl4 and compared with silymarin as references.

Chemical profiling of leaf essential oil, Antioxidant potential and Antibacterial activity of Syzygium lanceolatum (Lam.) Wt. &Arn. (Myrtaceae)

Introduction: The present study was aimed to analyse the chemical composition, antioxidant potential and antibacterial activity in the leaf essential oil of Syzygium lanceolatum Methods: The

Antioxidant activities of leaf extracts of Euphorbia fusiformis Buch. -Ham. ex D. Don (Euphorbiaceae)

Introduction: Free radicals such as reactive oxygen species (ROS) and reactive nitrogen species (RNS) are known to causes damage to the cellular biomolecules, resulting degenerative diseases.

Evaluation of Antioxidant Activities of Alpinia galanga (L.) Willd

Present research was designed to evaluate the free radical scavenging capacities and antioxidant activities of rhizome extracts of Alpinia galanga prepared in different solvent systems (60% aqueous




Objective: The present study was designed for isolation of bioactive polyphenolic compounds from methanol extract of Azolla microphylla and their subsequent characterization. Methods: The flavonoid

Free-radical-scavenging principles from Phlomis caucasica

Seven free-radical-scavenging phenolic compounds including five flavonoids, rutin, and two phenylethanoid glycosides, forsythoside B and acteoside, were isolated from the methanol extract of the aerial parts of the Iranian medicinal plant Phlomis caucasica by reversed-phase preparative high-performance liquid chromatography (HPLC).

Identification of the antioxidant principles of Polyalthia longifolia var. pendula using TEAC assay

This is the first study on the antioxidant activity of this plant species and it was found that the activity of the active fraction was due to quercetin and its glycosides, with TEAC values of 4.10, 1.91 and 2.38 mM, respectively, while the kaempferol glycoside were found to be inactive.

Chemical Constituents and Cytotoxic activity of Cassia glauca Lan . Leaves

The defatted 85 % methanolic extract from the leaves of Cassia gluaca Lan. (Family Leguminaceae) showed high cytotoxic effect against liver carcinoma cell line (HepG2) (IC50 = 17 μg /ml). Therefore

Phytochemical screening and in vitro evaluation of free radical scavenging activity of Cordia macleodii bark. (HOOK.F. & THOMSON)

Antioxidant activity has been assessed by in vitro method for phytochemical fraction of plant, viz. methanolic and butanol extracts of Cordia macleodii bark. This investigation was under taken to

In vitro anti-oxidant activity of Ruellia tuberosa root extracts

The EAFME of root showed the highest concentration of phenolic, flavonoid content, free radical scavenging activity and reducing power and was concluded that the R tuberosa root possess anti-oxidant activity.

Studies on phytochemical and In-Vitro antioxidant potential of Justicia beddomei (Clarke) Bennett

Introduction: The current study was carried out to investigate the phytochemical constituents and in vitro antioxidant potential of the aerial parts of Justicia beddomei (Clarke) Bennett belonging to

Antioxidant capacity and phenolic content of Elaeagnus kologa schlecht. an underexploited fruit from India

Introduction: In this study, assessment of total phenolic and flavonoid contents and antioxidant capacity of methanolic extract of fruits of Elaeagnus kologa Schldl. were examined for the first time.

Free Radical Scavenging Activity of Leaves of Memecylon edule Roxb

The aqueous extract of Memecylon edule showed significant free radical scavenging potential compared to the ethanolic extract, and can provide efficient antioxidant protection by complementary mechanisms, such as freeradical scavenging and metal ions reduction with the non polar extracts.