Antioxidant capacity and structural changes of human serum albumin from patients in advanced stages of diabetic nephropathy and the effect of the dialysis

@article{RosasDaz2015AntioxidantCA,
  title={Antioxidant capacity and structural changes of human serum albumin from patients in advanced stages of diabetic nephropathy and the effect of the dialysis},
  author={Marisol Rosas-D{\'i}az and Menandro Camarillo-Cadena and Andr{\'e}s Hern{\'a}ndez-Arana and Eva Ram{\'o}n-Gallegos and Rafael Medina-Navarro},
  journal={Molecular and Cellular Biochemistry},
  year={2015},
  volume={404},
  pages={193-201}
}
Changes in the antioxidant capacity of albumin and alterations of the albumin structural conformation were examined in patients in advanced stages of diabetes nephropathy. Human serum albumin was purified from diabetic patients in pre-dialysis (glomerular filtration rate [GFR] between 15 and 29 ml min−1 1.73 m−2) and those in dialysis (GFR ≤ 15 ml min−1 1.73 m−2) and then compared with albumin from patients with a normal GFR (>90 ml min−1 m−2). We evaluated the antioxidant capacity of albumin… 
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