Antioxidant and neuroprotective properties of N-arachidonoyldopamine

@article{Bobrov2008AntioxidantAN,
  title={Antioxidant and neuroprotective properties of N-arachidonoyldopamine},
  author={M. Bobrov and A. Lizhin and E. Andrianova and N. Gretskaya and V. Bezuglov},
  journal={Neuroscience Letters},
  year={2008},
  volume={431},
  pages={6-11}
}
N-Acyldopamines were recently described as putative endogenous substances in the rat brain. Among them, N-arachidonoyldopamine (AADA) was characterized as cannabinoid CB1 and vanilloid TRPV1 receptor ligand. The physiological significance of such compounds is yet poorly understood. In this study, we describe the novel properties of AADA as antioxidant and neuroprotectant. Antioxidant potential of AADA and its analogs were first tested in the galvinoxyl assay. It was found that N-acyldopamines… Expand
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