Antioxidant and anti-inflammatory activities of the plant Andrographis paniculata Nees.

  title={Antioxidant and anti-inflammatory activities of the plant Andrographis paniculata Nees.},
  author={K Mony Sheeja and Puthiyaveetil Kochumon Shihab and Girija Kuttan},
  journal={Immunopharmacology and immunotoxicology},
  volume={28 1},
In this study, we explored the antioxidant and anti-inflammatory properties of the medicinal herb Andrographis paniculata using in vitro as well as in vivo systems. Methanolic extract of Andrographis paniculata was found to inhibit formation of oxygen derived free radicals such as superoxide (32%) hydroxyl radicals (80%) lipid peroxidation (80%) and nitric oxide (42.8%) in in vitro system. In vivo studies using BALB/c mice models also showed significant inhibition in PMA induced superoxide (32… CONTINUE READING


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