Antioxidant and ACE enhancing potential of Pankajakasthuri in fluoride toxicity: An in vitro study on mammalian lungs

  title={Antioxidant and ACE enhancing potential of Pankajakasthuri in fluoride toxicity: An in vitro study on mammalian lungs},
  author={Rupal A. Vasant and Mona C Khajuria and A. V. R. L. Narasimhacharya},
  journal={Toxicology and Industrial Health},
  pages={793 - 801}
  • Rupal A. Vasant, Mona C Khajuria, A. V. R. L. Narasimhacharya
  • Published 2011
  • Chemistry, Medicine
  • Toxicology and Industrial Health
  • Fluoride toxicity occurs due to high concentrations of fluoride in water sources or anthropogenic causes. The aim of the present study was to investigate the effects of an Ayurvedic drug—Pankajakasthuri (PK)—in relation to fluoride-induced toxicity in mammalian lungs. The results indicated that sodium fluoride increased lipid peroxidation and decreased enzymatic and non-enzymatic antioxidants in a concentration-dependent manner in lungs. The antioxidant potential of the lungs was suppressed… CONTINUE READING
    9 Citations
    Coal-burning endemic fluorosis is associated with reduced activity in antioxidative enzymes and Cu/Zn-SOD gene expression
    • 9
    • Highly Influenced
    Lung damage after long-term exposure of adult rats to sodium fluoride
    • 12
    • PDF
    Pulmonary fluorosis: a review
    • 3
    Ethnopharmacological Use and Biological Activities of Tragia involucrata L.


    Effect of fluoride intoxication on lipidperoxidation and antioxidant status in experimental rats.
    • 208
    Lipid peroxidation and antioxidant systems in the blood of young rats subjected to chronic fluoride toxicity.
    • 47
    • PDF
    Effects of the Phenolic Contents of Mauritian Endemic Plant Extracts on Promoter Activities of Antioxidant Enzymes
    • 61
    Mode of action of sesame lignans in protecting low-density lipoprotein against oxidative damage in vitro.
    • 96
    Antioxidant activity of glycowithanolides from Withania somnifera.
    • 292
    Phenolic antioxidants: a rationale for design and evaluation of novel antioxidant drug for atherosclerosis.
    • 174
    Dietary defatted sesame flour decreases susceptibility to oxidative stress in hypercholesterolemic rabbits.
    • 105
    • PDF
    Sesamolin inhibits lipid peroxidation in rat liver and kidney.
    • 136
    • PDF