Antioxidant activity and hypoglycemic effect of ferulic acid in STZ-induced diabetic mice and KK-Ay mice.

@article{Ohnishi2004AntioxidantAA,
  title={Antioxidant activity and hypoglycemic effect of ferulic acid in STZ-induced diabetic mice and KK-Ay mice.},
  author={Masami Ohnishi and Tatuki Matuo and Takuo Tsuno and Asao Hosoda and Eisaku Nomura and Hideki Taniguchi and Hajime Sasaki and H. M. Morishita},
  journal={BioFactors},
  year={2004},
  volume={21 1-4},
  pages={315-9}
}
Antioxidant activity and biological properties of ferulic acid (FA) are well recognized. This study was designed to estimate the potential utility of FA administered orally at low dosage for improvement of hyperglycemia in diabetes. With this aim we have evaluated the hypoglycemic effect of FA in two type diabetic animal models: (1) streptozotocin (STZ)-induced diabetic mice, a model of insulin-dependent diabetes mellitus (IDDM); (2) KK-Ay mice, a model of non-insulin dependent diabetes… CONTINUE READING

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