Antioxidant activities of some tryptophan metabolites: possible implication for inflammatory diseases.

@article{Christen1990AntioxidantAO,
  title={Antioxidant activities of some tryptophan metabolites: possible implication for inflammatory diseases.},
  author={Stephan Christen and Ernst Peterhans and R Stocker},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1990},
  volume={87 7},
  pages={2506-10}
}
The antioxidant properties of tryptophan and some of its oxidative metabolites were examined by measuring how efficiently they inhibited peroxyl radical-mediated oxidation of phosphatidylcholine liposomes and B-phycoerythrin. Low micromolar concentrations of 5-hydroxytryptophan, 3-hydroxykynurenine, xanthurenic acid, or 3-hydroxyanthranilic acid, but not their corresponding nonhydroxylated metabolic precursors, scavenged peroxyl radicals with high efficiency. In particular, 3-hydroxykynurenine… CONTINUE READING
70 Extracted Citations
0 Extracted References
Similar Papers

Citing Papers

Publications influenced by this paper.
Showing 1-10 of 70 extracted citations

Similar Papers

Loading similar papers…