Antioxidant-Rich Woodfordia fruticosa Leaf Extract Alleviates Depressive-Like Behaviors and Impede Hyperglycemia

  title={Antioxidant-Rich Woodfordia fruticosa Leaf Extract Alleviates Depressive-Like Behaviors and Impede Hyperglycemia},
  author={Mohammed Abu Tayab and Kazi Ashfak Ahmed Chowdhury and Mohammed Sahek. Ullah Jabed and Syed Mohammed Tareq and A.T.M. Mostafa Kamal and Mohammad Nazmul Islam and Afaz Uddin and Mohammad Adil Hossain and Talha Bin Emran and Jes{\'u}s Simal-G{\'a}ndara},
Dhaiphul (Woodfordia fruticosa) is a frequently demanded plant in South-East Asian regions for its diverse medicinal values. This study was proposed to examine antioxidant, antidiabetic, and antidepressant potentials of methanol extract of W. fruticosa leaves (MEWF) and its derived n-hexane (NHFMEWF) and ethyl acetate (EAFMEWF) fractions through in vitro, in vivo, and computational models. Among test samples, MEWF and EAFMEWF contained the highest phenolic content and showed maximal antioxidant… 

Evaluation of Antioxidant, Cytotoxic, Anti-Inflammatory, Antiarthritic, Thrombolytic, and Anthelmintic Activity of Methanol Extract of Lepidagathis hyalina Nees Root

The present investigation suggests that L. hyalina could be the best choice for the management of cardiovascular, inflammation, arthritis, and anthelmintic diseases.

Investigation of the Pharmacological Properties of Lepidagathis hyalina Nees through Experimental Approaches

The current study suggests that L. hyalina could be a potential source of anti-oxidative, cytotoxic, thrombolytic, anxiolytic and antidepressant agents.

Identification of α-amylase inhibitors from flavonoid fraction of Feronia elephantum and its integration with in-silico studies

In-vitro α-amylase inhibitory activity of the flavonoid-rich fraction of the fruit pulp of Feronia elephantum may be due to the presence of vitexin, predicted via in-silico molecular docking; further, which needs to be further validated through in-vivo protocols.

Ethnomedicinal Value of Antidiabetic Plants in Bangladesh: A Comprehensive Review

The present review amasses a list of ethnomedicinal plants of 143 species belonging to 61 families, from distinctive domestic survey literature, reported to have been used to treat diabetes by the ethnic and local people of Bangladesh.

Synthesis and biological activities of alcohol extract of black cumin seeds (Bunium persicum)-based gold nanoparticles and their catalytic applications

Abstract Fast, simple, and environmentally friendly gold nanoparticles (Au-NPs) capped and stabilized with black cumin (Bunium persicum) seed alcohol extract are reported. The aqueous gold ions

Bromelain a Potential Bioactive Compound: A Comprehensive Overview from a Pharmacological Perspective

Bromelain is an effective chemoresponsive proteolytic enzyme derived from pineapple stems. It contains several thiol endopeptidases and is extracted and purified via several methods. It is most

Natural plant products as effective alternatives to synthetic chemicals for postharvest fruit storage management.

Fruits contain enormous source of vitamins that provides energy to the human body. These are also affluent in essential and vital vitamins, minerals, fiber, and health-promoting components, which has

Synthesis, Antioxidant, and Antidiabetic Activities of Ketone Derivatives of Succinimide

The prevalence of diabetes mellitus is persistently increasing globally creating a serious public health affliction. Diabetes mellitus is categorized into two major types designated as type I and

Novel Pharmacological Approaches to the Treatment of Depression

A brief history of clinically available antidepressants is provided, with a primary focus on novel pharmaceutical approaches with promising antidepressant effects in preclinical and clinical studies.



Pharmacological evaluation for anti-asthmatic and anti-inflammatory potential of Woodfordia fruticosa flower extracts

Woodfordia fruticosa flower (WFF) extracts exhibited anti-asthmatic effect by demonstrating bronchoprotection, bronchorelaxation, anti-inflammatory, antioxidant, and mast cell stabilization ability.

Pharmacological and computer-aided studies provide new insights into Millettia peguensis Ali (Fabaceae)

  • Safaet AlamN. Emon A. Ganguly
  • Biology
    Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society
  • 2020

Total Phenolic Content, Flavonoid Content and Antioxidant Potential of Wild Vegetables from Western Nepal

It is demonstrated that these wild edible leafy plants could be a potential source of natural antioxidants and a strong correlation between antioxidant activity with total phenolic and total flavonoid content was found.

Terpenoid content of Valeriana wallichii extracts and antidepressant‐like response profiles

Qualitative phytochemical analysis revealed that the aqueous‐ethanolic extract of V. wallichii was the only separated rhizome fraction containing terpenoids, suggesting that the antidepressant‐like action of this herbal plant is not contingent upon its terpenoid constituents.

Morus nigra and its major phenolic, syringic acid, have antidepressant-like and neuroprotective effects in mice

The results suggest that the antidepressant-like effect of MN, at least in part, could be due to the SA influence, and involves the nitro-oxidative system modulation in both the serum and brain of mice.

Antidepressant-like effect of the extract of Rosmarinus officinalis in mice: Involvement of the monoaminergic system

Evaluation of analgesic, anti-inflammatory, thrombolytic and hepatoprotective activities of roots of Premna esculenta (Roxb)

The results of the study demonstrated the antinociceptive, anti-inflammatory, thrombolytic and hepatoprotective activities of roots of P. esculenta.