Antioxidant Potential and Protection of Pancreatic ?- cells by Calotropis gigantea in Streptozocin Induced Diabetic Rats

@article{Choudhary2012AntioxidantPA,
  title={Antioxidant Potential and Protection of Pancreatic ?- cells by Calotropis gigantea in Streptozocin Induced Diabetic Rats},
  author={Naveen Kumar Choudhary and Swapnil Sharma and Arvind Kumar Jha and Manvendra Singh Karchuli and Jaya Dwivedi},
  journal={Journal of Complementary and Integrative Medicine},
  year={2012},
  volume={9}
}
This study was designed to examine the antioxidant defense by chloroform extract of Calotropis gigantea on streptozotocin-(40mg/kg, intraperitonial, single-injection) induced diabetes in wistar albino rats. The extract significantly (P < .05) decreased the pancreatic thiobarbituric acid-reactive substances (TBARS) levels and significantly (P < .05) increased the superoxide dismutase, catalase, and glutathione levels as compared to above levels in pancreatic tissue of pathogenic diabetic rats… Expand
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It was observed that the effect of chloroform extracts of Calotropis gigantea on alkaline phosphatase, cholesterol, superoxide dismutase, serum glutamic pyruvic transaminase, alkaline phosphate, cholesterol and triglyceride levels are comparable to that of those produced by the positive control. Expand
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