Antioxidant Mechanisms and ROS-Related MicroRNAs in Cancer Stem Cells

  title={Antioxidant Mechanisms and ROS-Related MicroRNAs in Cancer Stem Cells},
  author={Ilaria Dando and Marco Cordani and Elisa Dalla Pozza and Giulia Biondani and Massimo Donadelli and Marta Palmieri},
  booktitle={Oxidative medicine and cellular longevity},
Increasing evidence indicates that most of the tumors are sustained by a distinct population of cancer stem cells (CSCs), which are responsible for growth, metastasis, invasion, and recurrence. CSCs are typically characterized by self-renewal, the key biological process allowing continuous tumor proliferation, as well as by differentiation potential, which leads to the formation of the bulk of the tumor mass. CSCs have several advantages over the differentiated cancer cell populations… CONTINUE READING